Statins Inhibit Leukocyte Recruitment

Statins inhibit leukocyte recruitment: new evidence for their anti-inflammatory properties.

Properties Statins Inhibit Leukocyte Recruitment : New Evidence for Their Anti-Inflammatory Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2001 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Association, 7272 Arteriosclerosis, Thrombosis, and Vascular Biology 2001;21:1256-1258 Arterioscler Thromb Vasc Biol....

Class III antiarrhythmic methanesulfonanilides inhibit leukocyte recruitment in zebrafish.

Understanding fundamental molecular mechanisms that govern the transmigration and interstitial migration of leukocytes to sites of tissue damage and infection is of potential significance in identifying novel therapeutic targets for the management of chronic inflammatory disorders. CD31 is a mammalian cell adhesion molecule that regulates the recruitment of leukocytes from the circulation. Our ...

Lipophilic Statins Inhibit CD44 Fragmentation In Chondrocytes

Do Statins Inhibit Clopidogrel’s Antiplatelet Activity?

1 Pharmacy Times is proud to publish this new column on drug interactions by the esteemed Drs. Horn and Hansten, professors of pharmacy at the University of Washington and authors of the pocketsized drug interaction booklet The Top 100 Drug Interactions: A Guide to Patient Management and the loose-leaf reference Drug Interactions Analysis and Management. This column will appear monthly, and fee...

L-Selectin Shedding Regulates Leukocyte Recruitment

The physiologic role of L-selectin shedding is unknown. Here, we investigate the effect of L-selectin shedding on firm adhesion and transmigration. In a tumor necrosis factor alpha-induced model of inflammation, inhibition of L-selectin shedding significantly increased firm adhesion and transmigration by a lymphocyte function-associated antigen (LFA)-1 and intercellular adhesion molecule (ICAM)...